Dr. Bill Golde trained in basic immunology at Yale University and the University of Colorado studying the response of mice to sheep red blood cells and chicken ovalbumin, classic antigen systems of the day. After finishing a Ph.D. with John Kappler and Philippa Marrack, he completed postdoctoral training in molecular virology, studying HTLV 1 and 2. He entered the field of vaccine research joining the Centers for Disease Control and then Stony Brook University, working on a vaccine for Lyme disease, which was licensed for both human and canine. For the following 17 years, Dr. Golde led the immunology laboratory at the USDA’s Plum Island Animal Disease Center (PIADC), investigating immune responses of swine and cattle to foot-and-mouth disease virus (FMDV) infection. The Golde lab has developed new technologies to more closely track immune responses of swine and cattle, and using that information, have now designed new vaccine strategies to broaden the immune response to FMDV by targeting T cell responses. In 2016, Bill “retired” from USDA and moved to Edinburgh, Scotland to join the Moredun Research Institute. The techniques developed at USDA are now being applied to other critical diseases of cattle, sheep and swine including porcine reproductive and respiratory syndrome virus (PRRSV), African Swine Fever (ASF) virus, bovine herpes virus and bovine respiratory syncytial virus, while continuing work on new FMDV vaccines. Dr. Golde’s lab continues to expand and refine these technologies developed for livestock, leading to enhancing the assessment of vaccine performance.