Jin Huang

Dr
Jin
Huang

Senior Scientist
Tiba Biotech, LLC
Biography

EDUCATION/TRAINING: 1) Huazhong Agricultural University, Wuhan, China. Degrees: DVM and MS (Veterinary Pathology), in 1991. 2) Auburn University, Auburn, Alabama, USA. Degree: PhD (Biomedical Sciences - Immunology), in 2000. 3) Harvard Medical School, Boston, Massachusetts, USA. Postdoc training completed in 2011 in the Department of Microbiology and Molecular Genetics (current  

POSITIONS: 
• 1991-1996, Assistant Research Investigator, China Agricultural University Institute of Laboratory Animal Sciences. Areas of experience: Development and clinical evaluation of vaccines and immunological methods of diagnosis for animal infectious diseases.
• 1996-2000, Graduate Research Assistant, Auburn University. Areas of experience: Development and pre-clinical evaluation of DNA vaccines for human and animal infectious diseases caused by Chlamydia.
• 2001-2011, Research Fellow, Harvard University. Areas of experience: post-genomics vaccine candidate discovery for human infectious diseases.
• 2012-2018, Molecular Biologist, Agrivida, Inc. Areas of experience: Protein engineering and multiplex mediator probe-based real-time PCR for gene analysis and genotyping. 
• 2018-now, Senior Scientist, Tiba Biotech, LLC. Areas of experience: Development of mRNA Vaccines and therapeutics.

HONORS AND AWARDS:
• Graduate Academic Excellence from Auburn University, USA, 1998.
• Outstanding International Graduate Student from Auburn University, USA, 2000.
• Research Award from Epsilon Chapter of Phi Zeta National Honor Society of Veterinary Medicine, USA, 2001.
• Research Award from Epsilon Chapter of Phi Zeta National Honor Society of Veterinary Medicine, USA, 2003.

PROFESSIONAL MEMBERSHIPS:
• AMERICAN ASSOCIATION OF IMMUNOLOGISTS (AAI)
• AMERICAN SOCIETY FOR MICROBIOLOGY (ASM)

SELECTED PUBLICATIONS:
1. Weihui Wu, Huang J, Traficante DC, Hong H, Lory S and Priebe PG (2012) Novel Pseudomonas aeruginosa vaccines based on screening for Th17-stimulating protein antigens. American Journal of Respiratory and Critical Care Medicine (186): 420-427.
2. Aiello D, Williams JD, Majgier-Baranowska H, Patel I, Peet NP, Huang J, Lory S, Bowlin TL and Moir DT (2010) Discovery and characterization of inhibitors of Pseudomonas aeruginosa type-III secretion. Antimicrobial Agents and Chemotherapy 54(5): 1988-99.
3. Montor WR, Huang J, Hu Y, Hainsworth E, Lynch S, Kronish JW, Ordonez CL, Logvinenko T, Lory S and LaBaer J (2009) A genome-wide study of Pseudomonas aeruginosa outer membrane protein immunogenicity using self-assembling protein microarrays. Infection and Immunity 77(11): 4877-86.
4. Huang J, Lesser C & Lory S. (2008) The essential role of the CopN protein for Chlamydia pneumoniae intracellular growth. Nature 456 (7218): 112-115.
5. Lee VT, Pukatzki S, Sato H, Kikawada E, Kazimirova AA, Huang J, Li X, Arm JP, Frank DW & Lory S. (2007) Pseudolipasin A is a specific inhibitor for phospholipase A2 activity of Pseudomonas aeruginosa cytotoxin. Infection and Immunity 75(3): 1089-1098.
6. Stemke-Hale K, Kaltenboeck B, Degraves FJ, Sykes KF, Huang J, Bu CH & Johnston SA. (2005) Screening the whole genome of a pathogen in vivo for individual protective antigens. Vaccine 23(23): 3016-3025.
7. Huang J, DeGraves FJ, Lenz SD, Gao D, Feng P, Li D, Schlapp T & Kaltenboeck B. (2002) The quantity of nitric oxide released by macrophages regulates Chlamydia-induced disease. Proceedings of the National Academy of Sciences of the United States of America 99(6): 3914-3919.
8. Huang J, DeGraves FJ, Gao D, Feng P, Schlapp T & Kaltenboeck B. (2001) Quantitative detection of Chlamydia spp. by fluorescent PCR in the LightCycler. BioTechniques 30(1): 150-157.
9. Huang J, Wang MD, Lenz SD, Gao D & Kaltenboeck B. (1999) IL-12 administered during Chlamydia psittaci lung infection in mice confers immediate and long-term protection and reduces macrophage inflammatory protein-2 level and neutrophil infiltration in lung tissue. The Journal of Immunology 162(4): 2217-2226.
10. Huang J, Chen DW, Zhang B & Li J. (1996) Development and application of an ELISA kit for detecting avian leukosis virus antigen. Chinese Journal of Veterinary Medicine 20(4): 3-5.

Research interests

My interest is to develop a new generation of vaccines and immunotherapies for human and animal diseases.