Dr
Nguyen
Nhien
2/2013 - present – Lacturer, Faculty of Veterinary Medicine, Vietnam National University of Agriculture
4/2017 - 3/2020 – JICA long-term Ph.D. trainee, Tokushima University
4/2019 - 2/2020 – Research Assistant, Tokushima University
3/2020 - now – Lacturer, Faculty of Veterinary Medicine, Vietnam National University of Agriculture
My research will use porcine organs as favorable resources for xenotransplantation, using their advantages such as similarity to human organs in size and function, and can be bred in large quantity.
I plan to work on creating new species of genetically engineered pigs, suitable for solid organ transplants (kidney, liver, heart, lung, intestine, and pancreas) for patients with endocrine disorders such as diabetes.
For gene editing, I will use well-established methods such as CRISPR/Cas9 gene editing, using plasmid via microinjection, editing embryos zona pellucida free via chemistry, etc., as well as trying to develop new protocols and techniques to enhance the efficiency of the process of introduction of desirable gene-editing components in vitro.
I also interested in working on genetic experiments that potentially could contribute to the resurrection of extinct animals.
The other aim I will create cell lines for research, especially to create iPS cells of primate animals, endangered animals or domestic animals eg pigs, cows, etc., for research. For example, production by interspecies somatic cell nuclear transfer or interspecies Chimerism with induced pluripotent stem cells.