My expertise in immunology was laid by research on local and systemic immune responses to infectious diseases in cattle and pigs, and development of agent-specific tests to measure humoral and cell-mediated immune responses. Over the years I have developed purified antigens, anti-cytokine antibodies, and applied direct identification of peptide-specific cytotoxic T cells by staining with recombinant produced MHC-peptide tetramer complexes. With a focus on immunology I have worked with Foot-and-mouth disease, paratuberculosis (Mycobacterium paratuberculosis), ascariosis (Ascaris suum and Ascaridia galli), brucellosis (B. suis), yersiniosis (Y. enterocolitica O:9), porcine Mycoplasma arthritis (M. hyosynoviae), porcine proliferative enteropathy (Lawsonia intracellularis), chlamydiosis (C. trachomatis), toxoplasmosis (T. gondii), SARS-CoV-2, and enterotoxigenic E. coli.

Most recently my research has focused on targeting mucosal surfaces through novel vaccine technologies and apply these in vaccine development in veterinary and human medicine.