Noah Okumu

Dr
Noah
Okumu

Research Associate
International Livestock Research Institute
Biography
Currently, I am engaged in contagious bovine pleuropneumonia (CBPP) research, focusing on disease scoping to identify prevalence, assessing vaccine efficacy and field challenges, developing transmission models to understand herd-level spread, and creating infection models for vaccine trial experiments. My earlier research has been dedicated to preserving the genetic resources of native chicken ecotypes by exploring genetic diversity and enhancing resistance to viral diseases through gene construct injection into chicken primordial germ cells. Previously, I employed a One Health approach to investigate the epidemiology of antimicrobial resistance (AMR) in children and household animals in rapidly urbanizing peri-urban areas that are hotspots for AMR emergence. This work emphasized the role of food systems in AMR transmission and addressed the unique challenges of resource-limited environments.
Research interests
1. Contagious Bovine Pleuropneumonia (CBPP) and Vaccine Development: • Investigating CBPP epidemiology and disease prevalence in livestock populations. • Assessing vaccine efficacy, addressing field challenges, and improving immunological responses. • Developing transmission models to understand CBPP spread and designing infection models for experimental vaccine trials. • Identifying correlates of protection to enhance vaccine effectiveness in livestock diseases. 2. Poultry Genetics and Viral Disease Resistance: • Preserving genetic resources of indigenous chicken ecotypes. • Enhancing resistance to viral diseases through genetic engineering, such as gene construct injection into primordial germ cells. • Exploring genetic diversity to inform breeding strategies for local poultry populations. 3. One Health and Antimicrobial Resistance (AMR): • Investigating AMR at the human-animal-environment interface in peri-urban and resource-limited settings. • Exploring the role of food systems in the transmission and emergence of AMR. • Developing context-specific, integrated One Health strategies to mitigate AMR and its public health impact.
Projects you're working on
Contagious Bovine Pleuropneumonia (CBPP) disease scoping to identify disease prevalence, CBPP vaccine quality survey, CBPP transmission models to understand how the disease spreads within herds, development of CBPP infection models for vaccine trial experiments
Discipline
Bacteriology Bioinformatics Cellular biology Challenge model development Challenge study design Epidemiology Immunology – B-cells Immunology – T-cells Immunology – innate Molecular biology
Host species
Cattle Poultry Small ruminants
Pathogen
Bacteria BacteriaE. coli BacteriaMycoplasma BacteriaSalmonella Viruses VirusesArboviruses
Stage of vaccine development
Antigen discovery and immunogen design Correlates of protection – immunomonitoring