Thu Dung Doan

Dr
Thu Dung
Doan

Assistant Professor
International Degree Program in Animal Vaccine Technology, National Pingtung University of Science and Technology, Taiwan
Biography

1. National Pingtung University of Science and Technology-Taiwan, General Research Service Center- Assistant professor rank research fellow
(2020.10~2023.07) 
2. Animal Drugs Inspection Branch, Animal Health Research Institute, Miaoli, Taiwan - Internship
(2017.8~2017.9)
3. National Pingtung University of Science and Technology, Taiwan- Graduate Institute of Animal Vaccine Technology- Research Assistant
(2015.9~2016.7)
4. Viet A Technology Corporation, Vietnam-R&D Department - Technical staff
(2012.9~2013.7)
5. Institute of Veterinary Research and Development (IVRD) of central Viet Nam - Internship
(2012.1~2012.6)

Research interests

Nucleic acid technology: DNA/RNA extraction, PCR, qPCR, cloning Protein techniques: Protein analysis, protein expression, SDS-PAGE, western blot, and protein purification. In vitro: Cell culture, bioreactor, roller bottle Animal models: Mice, chickens, ducks, porcine, goats, bovines, fish Animal vaccines and adjuvants: Inactivated, subunit, DNA vaccines, biological adjuvants (TLR4, TLR5), monoclonal antibody, IgY. Immune evaluations: ELSIA, flow-cytometry, T cell proliferation, HA, HI, dot blot, neutralization.

• Yao-Chi Chung, Li-Ting Cheng, Chun-Yen Chu, Haroon Afzal and Thu-Dung Doan*. Flagellin enhances the immunogenicity of Pasteurella multocida lipoprotein E subunit. Avian Disease. 2024. • Li-Ting Cheng, Chun-Yen Chu, Hung Vu-Khac and Thu-Dung Doan*. Signal sequence contributes to the immunogenicity of Pasteurella multocida lipoprotein E. Poultry Science. 2023. • Asad Murtaza, Haroon Afzal, Thu-Dung Doan, Guan-Ming Ke and Li-Ting Cheng*. Flagellin Improves the Immune Response of an Infectious Bursal Disease Virus (IBDV) Subunit Vaccine. Vaccines. 2022. • Min-Chia Wu1, Thu-Dung Doan1, Jai-Wei Lee, Yi-Ting Lo, Hsing-Chieh Wu and Chun-Yen Chu*. Recombinant suilysin of Streptococcus suis enhances the protective efficacy of an engineered Pasteurella multocida toxin protein. Research in Veterinary Science. 2022. • Thu-Dung Doan, Hsian-Yu Wang, Guan-Ming Ke and Li-Ting Cheng*. N-terminus of Flagellin Fused to an Antigen Improves Vaccine Efficacy against Pasteurella multocida Infection in Chickens. Vaccines. 2020.
Projects you're working on
• Cloning and expression of truncated Streptococcus suis suilysin, along with Protein Anchor as an immunostimulant adjuvant for vaccine development (2024/1/1 -2024/12/31) • Study on the expression levels of the truncated domain of duck egg drop syndrome virus (DEDSV) Envelope (E) protein in a prokaryotic system (2020/1/1 -2020/12/31) • Identification and phylogenetic analysis of a novel duck parvovirus in Viet Nam (2021/1/1 – 2021/12/31) – Role: PI The effects of Cinnamomum osmophloeum Kanehira leaves extraction in animal vaccine development (2021/1/1 - 2021/12/31) • Evaluation of antibacterial agents effectiveness (2021/1/1 -2021/12/31) • Analysis of antibacterial materials (2022/5/1 -2023/7/31) • Development of new generation vaccines against swine coronavirus (2021/1/1 - 2023/12/31) • Establish methods of functional nanoparticle synthesis technology (I) (2023/1/1 - 2023/12/31) • Immunostimulatory evaluation of extracts (II) (2023/1/1 - 2023/12/31)
Discipline
Immunology – B-cells Immunology – T-cells Immunology – innate Molecular biology Parasitology Protein biology Virology
Host species
Cattle Pigs Poultry
Pathogen
Bacteria Bacteria›E. coli Viruses Viruses›Classical swine fever virus
Stage of vaccine development
Adjuvants Antigen discovery and immunogen design Clinical trials Vaccine delivery