Lynda Coughlan

Dr
Lynda
Coughlan

Assistant Professor
University of Maryland School of Medicine
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Biography

My research focuses on developing novel vaccines for infectious disease based on non-replicating adenoviral (Ad) vectors and an innovative approach called exosome-display technology. We also produce recombinant proteins for serology and immunisation studies. My PhD and early postdoctoral research was in the generation of genetically engineered oncolytic Ad vectors for cancer, and in developing non-human and rare species Ad vectors as vaccine vectors. More recently, I worked at the Jenner Institute, University of Oxford, where I was the lead immunologist on two Phase I clinical trials to evaluate novel chimpanzee Ad and poxviral vectors as "universal" influenza vaccines, and at Icahn School of Medicine at Mount Sinai in New York. I am now an independent PI with a laboratory based at the University of Maryland School of Medicine in Baltimore, USA. 

Research interests

Influenza, emerging viruses, coronaviruses, adenoviruses, RSV

Discipline
Protein biology Virology
Host species
Zoonoses
Pathogen
Viruses VirusesAdenovirus VirusesInfluenza virus VirusesRespiratory syncytial virus
Stage of vaccine development
Antigen discovery and immunogen design Pre-clinical trials