Bharti Mittal

Dr
Bharti
Mittal

Senior Bioinformatician
Pirbright Institute
LinkedIn 
View profile
Biography
As a seasoned professional, I bring a demonstrated track record of success in Bioinformatics/Computational Biology, encompassing Functional, System, and Structural analysis. My extensive experience in wet lab operations, coupled with adept team leadership, further strengthens my ability to deliver impactful results. I am driven by a passion for scientific discovery and innovation, and I am eager to leverage my skills and expertise to contribute meaningfully to the advancement of research. In my current role, I specialize in antibody sequence data analysis across a range of species, including Bovine, Pig, Rabbit, Chicken, Hybridoma, Human, and Mouse, utilizing NGS (Illumina & 10x) and Mass Spectrometry techniques. My responsibilities encompass BCR analysis from hybridomas, whole repertoire analysis, VDJ analysis from single-cell 10x data, and fishing antibody sequences from whole transcriptome data specific to Mycobacterium avium spp. in cattle. Additionally, I reconstruct antibodies from peptides generated from Mass Spectrometry data and conduct data mining from repositories such as NCBI, UniProt, IMGT, and species-specific immune databases to enhance antibody sequence analysis and interpretation.
Research interests
Antibody Repertoire Sequencing analysis
Discipline
Bioinformatics Immunology – B-cells Immunology – T-cells Immunology – innate Molecular biology Structural biology Systems biology Virology
Host species
Buffalo Camels Cattle Horses Pigs Poultry
Pathogen
BacteriaMycobacteria bovis Viruses VirusesAfrican swine fever virus VirusesBluetongue virus VirusesBovine viral diarrhoea VirusesInfluenza virus VirusesPorcine circovirus VirusesPorcine reproductive and respiratory syndrome virus VirusesRespiratory syncytial virus
Stage of vaccine development
Antigen discovery and immunogen design