Mark Stevens

Professor
Mark
Stevens

Chair of Microbial Pathogenesis and Deputy Director
The Roslin Institute, University of Edinburgh
Biography
Professor Mark Stevens is Chair of Microbial Pathogenesis at The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh. He was awarded a first class honours degree in Microbiology & Virology in 1992 before obtaining a Ph. D in Microbial Genetics in 1996. He rose from postdoctoral researcher to senior scientist at the Institute for Animal Health from 1999-2010, where he led the Enteric Bacterial Pathogens Laboratory before joining Roslin in 2011. His laboratory studies Salmonella, E. coli and Campylobacter infections in food-producing animals, with emphasis on the bacterial and host factors influencing the outcome of infections. He has contributed to understanding of how these bacteria colonise farmed animals, and has used this knowledge to design vaccines, therapies and strategies to breed animals that are resistant to infection. He has so far published over 170 peer-reviewed articles and secured 37 competitive grants totalling £15.7M. As Director of Research at Roslin since 2015, he has played a key role in securing strategic investment from the Biotechnology & Biological Sciences Research Council, totalling £42M for 2017-23 and £35.5M for 2023-28.
Research interests
Salmonella infections in chickens, pigs and cattle, including the molecular basis of persistence, pathogenesis and protection. Shiga toxin-producing E. coli in cattle and avian pathogenic E. coli in poultry. Campylobacter infections in chickens. I have devised and tested novel vaccines for each of these host-pathogen combinations.
Projects you're working on
At the time of writing, glycoconjugate vaccines for Campylobacter. live-attenuated vaccines for avian-pathogenic E. coli, and outer membrane vesicle-based Salmonella vaccines - all for poultry.
Discipline
Bacteriology
Host species
Cattle Pigs Poultry Zoonoses
Pathogen
Bacteria BacteriaE. coli BacteriaSalmonella
Stage of vaccine development
Antigen discovery and immunogen design