Angie Colston

Dr
Angie
Colston

Veterinary vaccine development consultant
Arpexas Ltd.
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Biography
Five years as a veterinary practitioner in large and small animal practice in the UK. Five years in molecular biology and immunopathology of Johnes disease in sheep as part of PhD thesis at R(D)SVS, Edinburgh and then post doctorate at the Moredun Research Institute in Edinburgh. Six years in Vaccine Research and Development with a portfolio of vaccines in cattle, sheep, dogs, avian including BVD, RSV, bovine leptospirosis, ovine chlamydia and paramyxovirus. Six years undertaking consultancy services in veterinary vaccine registration, development, clinical trials, expert reports and scientific writing. Two years as a consultant veterinary assessor for biologicals and pharmaceutical efficacy with Veterinary Medicines Directorate, UK. Five years as a Home Office Inspector ensuring compliance with Animals (Scientific Procedures) Act 1986. Four years at GALVmed,s Regional Director responsible for Research and Development on GALVmeds vaccine and therapeutics projects in SubSaharan Africa and SouthEast Asia.
Research interests
Mycobacteria, immunology and molecular biology, vaccinology, transboundary disease control. Porcine cysticercosis vaccinology, vaccine research and development particularly field trials, social science and disease control including one health. Cattle viral and bacterial respiratory diseases vaccine research and development (particularly BVD, RSV and BVD. Dog and cat vaccine regulatory compliance. Sheep chlamydia vaccines research and development.
Projects you're working on
General veterinary vaccine research and development consultancy
Discipline
Challenge model development Challenge study design Clinical trials – efficacy Clinical trials – safety Commercialisation Ethics Immunology – B-cells Immunology – T-cells Immunology – innate Molecular biology QC test development Quality assurance Registration Regulation Safety evaluation Social sciences Statistics Virology
Host species
Cats Cattle Dogs Horses Pigs Poultry Small ruminants Zoonoses
Pathogen
BacteriaBrucella BacteriaChlamydophila BacteriaLeptospira BacteriaMycobacteria bovis BacteriaMycoplasma BacteriaSalmonella ParasitesTaenia solium Viruses VirusesAfrican swine fever virus VirusesBovine viral diarrhoea VirusesFoot-and-mouth disease virus VirusesInfluenza virus VirusesNewcastle disease virus VirusesPeste des petits ruminants virus VirusesRabies virus VirusesRespiratory syncytial virus VirusesRift Valley fever virus VirusesRotavirus
Stage of vaccine development
Adjuvants Antigen discovery and immunogen design Clinical trials Correlates of protection – immunomonitoring Field trials Marketing Pre-clinical trials Vaccine delivery