Silvina Maidana

Dr
Silvina
Maidana

Licenciada en genética
IVIT (INTA-CONICET)
Biography
I obtained a degree in Genetics from the National University of Misiones in 2006. In 2008 I joined the working group of the Herpesvirus Vaccines and Pathogenesis Laboratory of the Institute of Virology, INTA-Castelar, from there I won scholarships that allowed me to obtain the title of Doctor from the UBA in 2014; year in which I also obtained a postdoctoral scholarship from CONICET. In 2015 I joined as an assistant researcher at CONICET where I work studying ruminant respiratory viruses, particularly herpesvirus, developing topics related to the characterization of strains and virulence studies of both wild and recombinant viruses. During the stage of doctoral student, Postdoc and assistant researcher we published numerous articles. From the results obtained during my doctoral thesis we published 8 articles, in 6 of which I have a leading role. Of these last articles, 5 were published in high-impact international journals. During my postdoc and research career, I published 10 articles, 2 in international journals and 8 in national journals. Of these last articles, I participated in 7 in a leading role. I also received grants as a researcher during my time as an assistant. During my time as an assistant researcher, my studies were directed at evaluating the occurrence of recombination events between related viruses. I directed several undergraduate theses and a doctoral thesis on this topic. I actively participate in collaborating with the lines of the group to which I belong, developing new serological and molecular diagnostic techniques for ruminant herpesvirus and parainfluenza virus 3 (PI3). Also in the in vitro/in vivo evaluation of molecules such as antivirals and immune response modulators. Manage and develop an active collaboration with a research group from Uruguay, demonstrated by the publication of joint articles. Also with different groups from Argentina belonging to INTA and national universities.
Research interests
Monitoring circulating BoHV-1 strains Escape from vaccine protection Genetic and antigenic identification of strains that evade vaccine immunity
Projects you're working on
Identification of new transmission routes of ruminant alphaherpesviruses Identification of recombinant viruses capable of escaping vaccine immunity Evaluation of the genetic diversity of ruminant alphaherpesviruses Cross-antigenicity tests between circulating alphaherpesvirus strains and the vaccine strain
Discipline
Bioinformatics Clinical trials – efficacy Epidemiology Molecular biology Virology
Host species
Buffalo Cattle
Pathogen
Viruses VirusesHerpesvirus VirusesParainfluenza virus
Stage of vaccine development
Antigen discovery and immunogen design Correlates of protection – immunomonitoring