Dr Mathers research interests are quite diverse and focus on several key areas within biochemistry, cell biology, and veterinary science. He has a strong background in molecular biology techniques, including protein expression and purification, cloning, and PCR. His work has also involved vaccine development and testing in animals, as well as Halaal sciences and testing. He has led strategic research programs in a multi-disciplinary environment, collaborating across various institutes. His supervision of specialist researchers from different science disciplines highlights his leadership in the field. Additionally, he has been involved in the development of diagnostic tests and disease surveillance, particularly for lumpy skin disease in cattle. His publications in peer-reviewed journals cover a range of topics, including the development of multivalent vaccines, the characterization of immunomodulatory gene knockouts, and the identification of antigens for diagnostic assays. He has also contributed to patents related to recombinant lumpy skin disease virus knock-out mutants. His research interests are centred around improving animal health through innovative vaccine development, diagnostic testing, and molecular biology techniques.