Mr
Alexsander
Moraes
Summary
Current position: PhD student in Basic and Applied Immunology at Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.
Supervisor: Dr. Beatriz Rossetti Ferreira.
Main research field: development of an epitope-based vaccine against Rhipicephalus microplus infestations in bovines.
Ongoing research activities:
a) development of recombinant subunit vaccines against R. microplus based on salivary antigens;
b) phage display and microarray-based epitope mapping of tick antigens.
Education
09/2020 - present: PhD student in Basic and Applied Immunology;
Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Project title: Development and evaluation of efficacy and immune response induced by multi-epitope vaccine formulations anti-tick Rhipicephalus microplus.
07/2018 - 08/2020: Master of Science - Basic and Applied Immunology;
Ribeirão Preto Medical School, University os São Paulo, Ribeirão Preto, São Paulo, Brazil.
Dissertation title: Identification of B and CD4+ T cell epitopes from salivary antigens of Rhipicephalus microplus in the construction of an anti-tick multi-epitope vaccine for bovines.
02/2013 - 12/2016: Bachelor of Biological Sciences;
University of Taubaté (UNITAU-SP), Taubaté, São Paulo, Brazil.
Monography: Identification of dengue 1 virus transovarial transmission in Aedes aegypti (Diptera: Culicidadae) larvae by means of RT-nested-qPCR.
Projects/Research
10/2017 - present: Development of an anti-tick vaccine for bovines. Intern from October 2017 until June 2018. Masters in Basic and Applied Immunology from July 2018 until August 2020. PhD student in Basic and Applied Immunology since September 2020.
02/2016 - 12/2016: Identification of dengue 1 virus transovarial transmission in Aedes aegypti larvae in a Brazilian city with high mosquito population density. Junior Scientific Initiation at the Laboratory of Molecular Biology by the Odontology Research Center (CEPEO), UNITAU-SP.
06/2014 - 12/2015: Genotoxicity and cytotoxicity analyses of water samples from the Paraiba do Sul River using bioassays. Junior Scientific Initiation at the Laboratory of Biology, UNITAU-SP.
Immunology, Molecular biology, Protein-based vaccines, Ticks, Epitope mapping, Omics, and Bioinformatics.
We are planning to produce our multi-epitope antigen on a vaccine platform based on virus-like particles.
Development of a recombinant multi-epitope vaccine against Rhipicephalus microplus tick using as vaccine platforms the soluble protein or associated to virus-like particles.
B and CD4+ T cell epitope mapping as potential anti-tick vaccine targets.