My role as a veterinary surgeon is t ensuring sustainable and safe animal production by supporting animal production societies. Animal infectious diseases are a major threat to animal production and welfare.  My research interest is to understand how different pathogens interact with the farm animal immune system to cause disease. My current Ph.D. research focuses on understanding the interaction of the cattle immune system against enteric food poisoning E.coli, Enteroheamorrahgic E.coli O157: H7. In my Ph.D. work, I investigated different immuno-epitopes identified by the host cellular response that may have an implication on the vaccine design. As the current vaccine available only provides short-term immunity and the probability of reinfection still exists, therefore I  identified the bacterial epitopes that can be included in the current vaccine that may enhance prolonged immunity. I am also interested in MHCI typing in different cows and buffaloes species and trying to understand the role of different types in determining the suitability or resistance to different diseases and how MHCI-types influences animal productivity. I am also interested in generating different cell lines expressing a defined MHC-I molecule by using traditional cloning and transfection methods besides CRISPR-Cas9 gene editing. Now, in my postdoctoral research, I am interested in understanding the bovine immune response against Theileria annulata is a tick-borne apicomplexan parasite widely distributed across low- and medium-income countries (LMICs). It causes bovine tropical theileriosis, a severe lymphoproliferative disease resulting in high mortality and heavy production losses, resulting in serious impacts on both animal health and welfare as well as the livelihoods of smallholders and farmers. Currently, available control measures have issues that detract from their usefulness: acaricides are expensive and there is emergence of drug-resistant tick populations; treatment with theileriacidal drugs provides incomplete protection; live attenuated vaccines are difficult to produce and deploy for a number of reasons. The shortcomings of each of these approaches highlight the need for alternative control strategies. As such, my current research focuses on identifying novel CD4+ T-cell antigens from Th annulata in order to accelerate the development of novel vaccines for this important livestock disease. This work involves establishing cell line infected with native Th.annulata stabilates to be used in identifying the CD4+ T cell epitopes using immunopeptidomics and mass spectrometry.