Henry Munyanduki

Dr
Henry
Munyanduki

Senior Postdoctoral Research Scientist
The Pirbright Institute
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Biography

I am passionate about projects aimed at controlling and possibly eradicating emerging transboundary diseases and I have significant experience (+7 years) working with lumpy skin disease virus (LSDV). I am highly experienced in using small animals and knowledgeable on the use of large animal models in research. I was a post-doctoral researcher at the Vaccine and Infectious Disease Organisation International Vaccine Centre (VIDO-INTERVAC). In that project, I looked at the viral dynamics of Zika virus and PCV2 in a porcine model. For the past few years, I have been a Senior Postdoctoral researcher at the Pirbright Institute. Here, I worked in the Arthropod Genetics Group in a project aimed at generating transgenic mosquitoes refractory to flaviviruses. I also worked in the Nidovirus Cell interactions group in coronavirus research where we were generating tools to study virus host interactions. More recently, I led the LSDV transmission studies under the supervision of Dr. Pip Beard. In this project, I am looking at the contribution of different hematophagous insects in the onward transmission of LSDV. My PhD training was in medical virology at the University of Cape Town, where I developed vaccine vectors for veterinary and human use. Prior to this, I obtained my MSc in Biomedicine from Hogskolan iSkovde, Sweden. I worked at the University of Queensland, Australia as a research assistant where I also conducted my master thesis. My project focused on unravelling the role of the immune system in nerve entrapment neuropathies using a rat model of dual nerve compression. My undergraduate training was in Applied Biology and Biochemistry and with an Honours research in Microbiology.

Research interests

My research interests are in virus-host/ virus-insect vector interactions. I also am interested in understanding proteins/gene products important in immunogen design and ultimately generating effective vaccines. 

Projects you're working on

LSDV transmission by blood feeding arthropods (BB/T1005173).

Discipline
Immunology – B-cells Immunology – T-cells Immunology – innate Molecular biology Virology
Host species
Buffalo Cattle Pigs Small ruminants Wildlife Zoonoses
Pathogen
Viruses VirusesArboviruses VirusesBovine ephemeral fever virus VirusesBovine viral diarrhoea VirusesCapripoxvirus VirusesClassical swine fever virus VirusesCoronavirus VirusesPorcine circovirus VirusesPoxviruses
Stage of vaccine development
Antigen discovery and immunogen design Correlates of protection – immunomonitoring