Swati Rani

Ms
Swati
Rani

Project Associate-I
ICAR-National Institute of Veterinary Epidemiology and Disease Informatics
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Biography

As a Bioinformatics specialist with a strong interest in vaccine design against important animal pathogens, I have a Master's degree in Bioinformatics from a reputable institution. During my studies, I developed expertise in data analysis, computational modeling, and statistical analysis, with a focus on using bioinformatics tools and techniques to better understand the biology of infectious diseases.

In particular, my research has focused on using bioinformatics approaches to design new vaccine formulations against livestock pathogens, such as lumpy skin disease virus (LSDV) and African swine fever virus (ASFV). I am particularly interested in the use of immunoinformatics and systems biology approaches to analyze large-scale genomic and proteomic data and identify new potential vaccine candidates against these viruses.

As a motivated and enthusiastic researcher, I am now looking for possible collaborations and PhD opportunities through the IVVN network that will allow me to further develop my skills and expertise in the field of animal vaccine design. I am excited to work with other researchers in the IVVN network to address key challenges in the field and develop novel vaccine strategies to combat important animal pathogens, which can have significant impacts on global food security and animal welfare.

Research interests

My research interest lies in the development and optimization of vaccines against important animal pathogens, with a particular focus on lumpy skin disease virus (LSDV) and African swine fever virus (ASFV). I use bioinformatics tools and techniques to analyze large-scale genomic and proteomic data and identify potential vaccine candidates, as well as to design novel vaccine formulations and delivery systems. I am also interested in the use of immunoinformatics and systems biology approaches to better understand the host-pathogen interactions involved in vaccine development and identify potential targets for vaccine design. My goal is to contribute to the development of effective and safe vaccines against LSDV, ASFV, and other animal pathogens, which can have significant impacts on global food security and animal welfare.

Projects you're working on

In my project work, I focused on the identification of potential vaccine candidates against lumpy skin disease virus (LSDV) and African swine fever virus (ASFV), two important animal pathogens. I used bioinformatics tools and techniques to analyze large-scale genomic and proteomic data and identify conserved and immunogenic epitopes that could be targeted by vaccine formulations. I also used computational modeling to design novel vaccine formulations and delivery systems that could enhance the immunogenicity and protective efficacy of LSDV and ASFV vaccines. My project work aimed to contribute to the development of effective and safe vaccines against these pathogens, which can have significant impacts on global food security and animal welfare.

Discipline
Bacteriology Bioinformatics Cellular biology Epidemiology Immunology – B-cells Immunology – T-cells Immunology – innate Molecular biology Parasitology Structural biology Systems biology Virology
Host species
Buffalo Cattle Pigs Zoonoses
Pathogen
Bacteria BacteriaBrucella BacteriaE. coli BacteriaMycobacteria bovis BacteriaMycoplasma BacteriaSalmonella ParasitesTaenia solium ParasitesTheileria annulata ParasitesTicks ParasitesTrypanosoma Viruses VirusesAdenovirus VirusesAfrican horse sickness virus VirusesAfrican swine fever virus VirusesBovine ephemeral fever virus VirusesBovine viral diarrhoea VirusesCalicivirus VirusesCapripoxvirus VirusesClassical swine fever virus VirusesCoronavirus VirusesFoot-and-mouth disease virus VirusesHerpesvirus VirusesInfectious bursal disease virus VirusesInfectious pancreatic necrosis virus VirusesInfectious salmon anaemia virus VirusesInfluenza virus VirusesNairoviruses VirusesNewcastle disease virus VirusesParvovirus VirusesPorcine circovirus VirusesPorcine reproductive and respiratory syndrome virus VirusesPoxviruses VirusesRabies virus VirusesRespiratory syncytial virus VirusesRetroviruses VirusesRift Valley fever virus VirusesRotavirus
Stage of vaccine development
Adjuvants Antigen discovery and immunogen design