Partial Protection of Goats against Haemonchus contortus Achieved with ADP-Ribosylation Factor 1 Encapsulated in PLGA Nanoparticles.

18 Oct 2024
Hasan MW, Gadahi JA, Haseeb M, Wang Q, Ehsan M, Lakho SA, Haider A, Aleem T, Lu M, Yan R, Song X, Li X, Xu L
(), a nematode with global prevalence, poses a major threat to the gastrointestinal health of sheep and goats. In an effort to combat this parasite, a nanovaccine was created using a recombinant ADP-ribosylation factor 1 (ARF1) antigen encapsulated within poly lactic-co-glycolic acid (PLGA). This study aimed to assess the effectiveness of this nanovaccine in providing protection against infection.